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Table 1 The 2x2 contingency table

From: Development and application of an interaction network ontology for literature mining of vaccine-associated gene-gene interactions

# of gene-gene

Concept-

Whole

Interaction pairs

specific sub-network

Network

With the INO term

30 – 1

500

Without the INO term

150

30000

  1. Note: The sub-network has 30 gene pairs associated with this INO term out of a total of 180 gene pairs. A modified Fisher’s exact test, with the “- 1” modification made to the typical Fisher’s exact test to make the statistical test more conservative, was employed to identify significantly over-represented terms (p-value of 6.9E-20).
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Journal of Biomedical Semantics

ISSN: 2041-1480