a) | MS-PCR revealed the [methylation] of the [p16] gene in 10 (34%) of 29 [NSCLCs] |
b) | 30% (27 of 91) of [lung tumors] showed [hypermethylation] of the 5’CpG region of the [p14ARF gene] |
c) | [Promotor hypermethylations] were detected in [O6-methylguanine-DNA methyltransferase (MGMT), RB1, estrogen receptor, p73, p16INK4a, death-associated protein kinase, p15INK4b, and p14ARF] |
d) | The promoter region of the [p16INK4] gene was [hypermethylated] in the tumor samples of the primary or metastatic site |