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Table 1 MayoGC Phase I studiesa,b (used with permission from Bielinski et al [[12]])

From: Applying semantic web technologies for phenome-wide scan using an electronic health record linked Biobank

Characteristics

eMERGE Network (PAD)[2]

GENEVA (VTE)[6]

PANC[7, 8]

 

Cases (n = 1612)

Controls (n = 1585)

Cases (n = 1233)

Controls (n = 1264)

Controls (n = 613)

Age (y), mean ± SD

66.0 ± 10.7

61.0 ± 7.4

55.0 ± 16.2

56.0 ± 15.8

66.0 ± 10.0

Female (%)

36

40

50

52

45

Medical record length (y)

Mean ± SD

23.4 ± 20.0

26.1 ± 20.3

13.7 ± 16.3

21.1 ± 15.4

30.2 ± 16.5

Median ± (range)

18.7 (1.0–78.6)

23.0 (1.0–79.2)

6.3 (1.0–71.8)

17.8 (1.0–70.2)

29.8 (1.0–75.0)

White (%)

94

94

96

99

100

Geographic location, No. (%)c

Olmsted Country

328(20)

590(37)

7(1)

10(1)

64(10)

Southeast Minnesota

191(12)

62(4)

205(17)

378(30)

107(17)

Greater Minnesota

393(24)

343(22)

314(25)

371(25)

135(22)

Iowa

212(13)

97(6)

176(14)

191(15)

65(11)

South and North Dakota

50(3)

31(2)

79(6)

71(6)

19(3)

Wisconsin

128(8)

68(4)

121(10)

138(11)

32(5)

Other states or international

309(19)

394(25)

330(27)

159(13)

191(31)

  1. aeMERGE=Electronic Medical Records and Genomics; GENEVA=Gene Environment Association Studies; MayoGC=Mayo Genome Consortia; PAD=peripheral arterial disease; PANC=Mayo Clinic Molecular Epidemiology of Pancreatic Cancer Study; VTE=venous thromboembolism.
  2. bPercentages may not total 100% because of rounding.
  3. cSoutheast Minnesota includes 7 counties in the southeast corner of Minnesota: Dodge, Goodhoue, Wabasha, Winona, Houston, Fillmore, and Mower, Olmsted County, Minnesota, is a mutually exclusive category.