Figure 6

Subset of Diseasecard’s integration graph. This seed takes advantage of COEUS’s flexible integration engine to acquire data from heterogeneous and distributed CSV, XML, SQL and SPARQL resources. The integration process generates a rich data network. For example, starting with Breast cancer in OMIM (114480) we obtain multiple genes from HGNC database (BRCA2, TP53…), which are used individually next to obtain a list of UniProt identifiers (P51587, P12830…). From UniProt data we also extract PharmGKB (PA30196, PA26282…) and PDB (2PCX, 1YCR…) identifiers, among others. This process continues until data is fully integrated for all resources in Diseasecard’s configuration.