Figure 1

Selected core VO terms relevant to the presented research. This figure shows a list of VO core terms relevant to the targeted study. VO is developed under the BFO framework. The VO term ‘vaccine component’ is a BFO ‘material entity’. A ‘vaccine’ is an OBI ‘processed material entity’. A ‘route of administration’ is a subclass of ‘BFO: site’. ‘vaccine-induced host response’, ‘vaccine-induced adaptive immune response’, ‘immunization’, ‘vaccine immunization’ and ‘vaccination’ are all processes, i.e., ‘processual entity’ in BFO. Note that ‘vaccination’ is asserted as ‘administering substance in vivo’ from OBI. Vaccination is the process of administering a vaccine into a host. It differs from vaccine immunization that is a biological process that starts at vaccination and results in an outcome of the host getting immunized.