Figure 4

Modelling the RB51-induced different immune response with different route administration. The upper part of this figure models the experimental results that interperitoneal RB51 vaccination in mice induced protection against virulent strain S2308 challenge in the lung[25]. The lower part of this figure models another study which showed that intranasal RB51 vaccination was unable to protect against virulent strain 2308 challenge in the lung as investigated in experiment 2[26]. Filled square boxes indicate class level terms. Boxes with round corners represent individual level data collected from papers.