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Table 2 Top 10 most significantly enriched biological functions for each gene-gene (i.e., ‘GG’) interaction network set

From: Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

Terms

Fever GG network

Vaccine fever GG network

VO fever GG network

regulation of cell death

45.5*

3.9

3.6

regulation of apoptosis

45.4*

3.9

3.6

regulation of programmed cell death

45.3*

3.9

3.6

response to organic substance

37.8*

3.4

3.9

response to wounding

36.7*

2.5

2.3

extracellular space

34.8*

1.0

1.0

positive regulation of multicellular organismal process

33.7*

3.1

3.9

defense response

33.6*

3.0

2.8

regulation of cell proliferation

31.6*

3.2

2.9

immune response

30.7*

7.8*

7.2*

cell activation

19.2

9.2*

8.7*

positive regulation of phosphorylation

16.6

7.2*

7.0*

positive regulation of phosphate metabolic process

16.3

7.2*

6.9*

positive regulation of phosphorus metabolic process

16.3

7.2*

6.9*

positive regulation of protein amino acid phosphorylation

15.3

7.3*

7.0*

leukocyte activation

14.3

7.3*

6.9*

leukocyte differentiation

9.7

8.9*

8.5*

hemopoiesis

9.6

7.3*

6.9*

lymphocyte differentiation

5.8

7.2*

6.9*

  1. Values are –log10(Benjamini-Hochberg corrected P-values) from DAVID results. * corresponds to the 10 lowest p-values in each set.
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Journal of Biomedical Semantics

ISSN: 2041-1480