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Table 5 Evaluation of performance increase of AUCiP/R

From: Ranking relations between diseases, drugs and genes for a curation task

PharmGKB data set

setting

mean

sd

Δ

Δabs

Δrel

p value

ΔCI l

Δrel bs

t-e0-r0-m0-n0-c0-s0

0.39

0.015

      

t-e1-r0-m0-n0-c0-s0

0.44

0.012

e1

+0.048

+12.1

9.8-4

+0.044

+12.1

t-e1-r0-m1-n0-c0-s0

0.49

0.014

m1

+0.044

+10.0

9.8-4

+0.042

+23.2

t-e1-r0-m1-n0-c1-s0

0.51

0.017

c1

+0.027

+5.5

9.8-4

+0.023

+30.0

tmc-e1-r0-m1-n0-c1-s0

0.53

0.015

tmc

+0.018

+3.4

9.8-4

+0.013

+34.5

tmc-e1-r1-m1-n0-c1-s0

0.54

0.015

r1

+0.012

+2.3

9.8-4

+0.010

+37.6

tmc-e1-r1-m1-n2-c1-s0

0.55

0.015

n2

+0.003

+0.6

9.8-4

+0.002

+38.4

tmc-e1-r1-m1-n2-c3-s1

0.55

0.013

c3-s1

+0.003

+0.5

1.5-2

+0.001

+39.1

tmc-e1-r1-m1-n3-c0-s1

0.55

0.014

n3-c0

+0.002

+0.4

1.4-2

+0.000

+39.7

CTD data set

setting

mean

sd

Δ

Δabs

Δrel

p value

ΔCI l

Δrel bs

t-r0-m0-n0-c0-s0

0.21

0.008

      

t-r0-m1-n0-c0-s0

0.30

0.006

m1

+0.090

+42.4

9.8-4

+0.087

+42.4

t-r0-m1-n0-c1-s0

0.37

0.009

c1

+0.072

+23.7

9.8-4

+0.068

+76.1

tmc-r0-m1-n0-c1-s0

0.41

0.026

tmc

+0.040

+10.6

2.0-3

+0.042

+94.9

tmc-r0-m1-n3-c1-s0

0.43

0.006

n3

+0.018

+4.3

2.9-3

+0.005

+103.3

tmc-r1-m1-n3-c1-s0

0.45

0.007

r1

+0.015

+3.5

9.8-4

+0.013

+110.4

tmc-r1-m1-n3-c3-s1

0.46

0.007

c3-s1

+0.012

+2.8

9.8-4

+0.009

+116.2

  1. This table gives the corresponding overview of feature-wise performance increase as in Table 4. See Table 4 for a detailed explanation on the interpretation of the columns.