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Table 5 Top 10 enriched cellular component terms in the profiling analysis of SCD patients

From: Enrichment analysis applied to disease prognosis

Acc

Name

p-value

p-Bonf

SFreq

PFreq

GO:0005859

Muscle myosin complex

2.4E-37

1.3E-35

81%

0.10%

GO:0032982

Myosin filament

2.4E-37

1.3E-35

81%

0.10%

GO:0016460

Myosin II complex

1.1E-35

5.8E-34

81%

0.13%

GO:0001725

Stress fiber

4.1E-20

2.2E-18

56%

0.25%

GO:0032432

Actin filament bundle

7.3E-20

3.8E-18

56%

0.27%

GO:0014705

C zone

9.2E-15

4.9E-13

25%

0.01%

GO:0005863

Striated muscle myosin thick filament

1.0E-12

5.4E-11

25%

0.02%

GO:0031672

A band

4.7E-09

2.5E-07

25%

0.13%

GO:0005861

Troponin complex

2.2E-05

1.1E-03

13%

0.04%

GO:0005865

Striated muscle thin filament

6.6E-05

3.5E-03

13%

0.07%

  1. The terms shown are the 10 cellular component terms with the lowest p-value, obtained in the profiling of SCD patients. For each term is indicated: GO accession number (Acc), term name, p-value without multiple-testing correction, p-value with Bonferroni correction (p-Bonf), annotation frequency in the study set (SFreq) and annotation frequency in the population set (PFreq).