Function of dynamic models in systems biology: linking structure to behaviour

Table 2 Formal approaches for functional aspects of bio-models

Functional aspect		Checklists	Languages	Ontologies
Teleological function
Intrinsic:	Intended use	MIASE	SED-ML	MINTENTO
Extrinsic:	Model use intention	Unknown	Unknown	MINTENTO
Conditional function
Intrinsic:	Model instantiation	MIASE	SED-ML	Not applicable
Extrinsic:	Boundary conditions	MIBBI	SABIO-RK^*	XCO
Pragmatical function
Intrinsic:	Setup	MIASE	SED-ML	KiSAO
Extrinsic:	Experimental settings	MIBBI	FuGE	MMO

^*The database scheme of SABIO-RK could be seen as a formal language for experimental conditions.

ISSN: 2041-1480