The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines

Table 2 Top 10 vaccines with the largest variety of VAEs reported

Vaccine (disease or pathogen)	VO_ID	Total # VAE
Recombivax HB (Hepatitis B)	VO_0010737	20
Comvax (Hib meningitis, Hepatitis B)	VO_0000028	19
Menactra (Neisseria meningitidis)	VO_0000071	18
Tetanus and Diphtheria Toxoids	VO_0000111	18
Absorbed by MA Biological
(Tetanus, Diphtheria)
Prevnar 13 (Streptococcus pneumonia)	VO_0000090	16
PedvaxHIB (H. influenzae type b)	VO_0000083	15
RabAvert (Rabies)	VO_0000094	14
JE-Vax (Japanese Encephalitis)	VO_0000066	13
Tetanus Toxoid (boost only) (Tetanus)	VO_0000984	13
Tetanus Toxoid Absorbed (Tetanus)	VO_0000048	13

Note: The disease or pathogen name specified next to a vaccine name indicates the disease or pathogen infection against which the vaccine is used. The three bacteria listed (shown by italicized words) can all induce meningitis. The vaccines are sorted based on the VAEs recorded in their package insert documents.