Figure 4

OAE classification of FluMist-associated adverse events (AEs). (A) Representation of those FluMist-associated adverse events (leave nodes) and their asserted hierarchy. (B) An OAE axiom defining equivalent class ‘respiratory system AE’. (C) Inferred hierarchy after reasoning using the HermiT reasoner available as a plugin in the Protégé-OWL editor in a Windows-7 computer. After reasoning, ‘respiratory system inflammation AE’ is classified as ‘respiratory system AE’. By comparing the places of the term ‘respiratory system inflammation AE’ (highlighted with red oval box) in (A) and (C), this term appears in both places in the inferred version in (C). This has not been moved, but an additional parent class has been added. It is noted that the execution of the reasoning was finished within seconds.