Network-based analysis reveals distinct association patterns in a semantic MEDLINE-based drug-disease-gene network

Table 1 Statistics of the six extracted association types

Association type	Record in Semantic MEDLINE	Unique associations	Associations involving FDA-approved drugs	Unique entity number
Disease-Disease	2,516,049	843,221	1684	2,248
Disease-Gene	206,155	111,117	21,444	5,954
Disease-Drug	3,021,256	1,277,879	54,996	3,414
Drug-Gene	398,572	248,491	3758	1,451
Drug-Drug	4,780,394	1,900,576	266	382
Gene-Gene	108,035	49,593	2169	2,792
Total	11,030,461	4,430,877	84,317	7,243¹

ISSN: 2041-1480