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Table 2 Coverage of AERS drugs by NDF-RT classes

From: Standardizing adverse drug event reporting data

Drug_class_type1 Drug_class, No.2 RxNormConcept, No. in the AERS3 a%4 b%5
Generic Ingredient Combinations 26 9,813 96 88
Chemical Ingredients Class 16 9,331 91 81
Therapeutic Intent 24 8,069 79 78
Mechanism of Action 7 8,061 79 81
Physiologic Effect 16 7,989 78 82
VA Class 29 5,823 57 77
FDA Established Pharmacologic Class (EPC) 66 3,049 30 46
Therapeutic Category 7 2,880 28 50
Pharmacokinetics 1 730 7 28
Total 192 10,221 100 100
  1. 1“Drug_class_type” represents various classes provided by NDF-RT as shown in Figure 2.
  2. 2“Drug_Class, No.” is the number of direct subordinate classes of each Drug_class_type.
  3. 3“RxNorm concept, No. in the AERS” shows the total number of RxNorm concepts in the AERS for each drug class type.
  4. 4“a%” indicates the percentage of classified RxNorm concepts for each Drug_class_type, calculated as the division of “RxNorm concept, No. in the AERS” by 10,221; a total of RxNorm concepts mapped to at least one NDF-RT class.
  5. 5“b%” indicates the percentage of classified AERS reports, calculated as the division of the number of AERS reports assigned with the Drug_class_type by the total AERS report number (2,643,979).