Skip to main content
Figure 5 | Journal of Biomedical Semantics

Figure 5

From: Nanopublications for exposing experimental data in the life-sciences: a Huntington’s Disease case study

Figure 5

First we queried the differentially expressed genes nanopublication to get all gene ids. Further we filtered these ids by querying the biological region nanopublication. Subsequently we queried the bio2RDF GO annotation dataset to select genes that are involved in the biological processes mentioned in the text. For this gene list we queried bio2RDF gene information data source to retrieve gene symbols that belong to the human taxonomy, that were used to retrieve the drug target from bio2RDF drugbank. Last, these drug targets are used to find drugs from the bio2RDF drugbank source. B. The process of querying GO for our set of biological processes(including the children concepts) and the mapping URI to filter genes from the bio2RDF GO annotation dataset. In this example we retrieve drug targets for one of the GO terms, autophagy.

Back to article page