Class | URI | Definition | subclass of | subclass of URI |
---|---|---|---|---|
chromatin_region | biosemantics:chromatin_region | A region of chromatin, likely to | biological_region | so:SO_0001411 |
be involved in a biological process | ||||
chromatin_state | biosemantics:chromantin_state | Annotation of chromatin states, defined by | feature_attribute | so:SO_0000733 |
combinations of chromatin modification patterns | ||||
(described in publication by Ernst et al. Nature, 2011) | ||||
active_promoter | biosemantics:active_promoter | Open chromatin region, associated with promoters, | chromatin_state | biosemantics:chromatin_state |
transcriptionally active, defined by the most highly | ||||
observed chromatin marks : H3K4me2,H3K4me3, H3K27ac, | ||||
H3K9ac | ||||
weak_promoter | biosemantics:weak_promoter | Open chromatin region, associated with promoters, | chromatin_state | biosemantics:chromatin_state |
weak transcription activity, defined by the most highly | ||||
observed chromatin marks : H3K4me1, H3K4me2,H3K4me3, | ||||
H3K9ac | ||||
poised_promoter | biosemantics:poised_promoter | Open chromatin region, associated with promoters, | chromatin_state | biosemantics:chromatin_state |
described as a bivalent domain that has strong signals | ||||
of both active and inactive histone marks. Most highly | ||||
observed histone marks: H3K27me3, H3K4me2, H3K4me3 | ||||
heterochromatic | biosemantics:heterochromatic | Closed chromatin formation, transcriptionally inactive. | chromatin_state | biosemantics:chromatin_state |
It is associated with none histone marks |