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Table 5 Top ATC Class Pairs

From: Evaluating drug-drug interaction information in NDF-RT and DrugBank

ATC Class Pair total DDIs NDF-RT only DrugBank only both Jaccard
Protease inhibitors - Protein kinase inhibitors 103 72 10 21 0.20
Benzodiazepine derivatives - Protease inhibitors 88 5 52 28 0.32
Adrenergic and dopaminergic agents - Non-selective monoamine reuptake inhibitors 78 0 78 0 0
Antibiotics - Other quaternary ammonium compounds 71 35 8 28 0.39
Penicillins with extended spectrum - Tetracyclines 63 0 58 5 0.08
Protein kinase inhibitors - Triazole derivatives 60 32 10 18 0.30
Beta blocking agents, non-selective - Sulfonamides, urea derivatives 56 10 14 32 0.57
Macrolides - Protein kinase inhibitors 56 27 14 15 0.27