Table 5 Top ATC Class Pairs
From: Evaluating drug-drug interaction information in NDF-RT and DrugBank
ATC Class Pair | total DDIs | NDF-RT only | DrugBank only | both | Jaccard |
|---|---|---|---|---|---|
Protease inhibitors - Protein kinase inhibitors | 103 | 72 | 10 | 21 | 0.20 |
Benzodiazepine derivatives - Protease inhibitors | 88 | 5 | 52 | 28 | 0.32 |
Adrenergic and dopaminergic agents - Non-selective monoamine reuptake inhibitors | 78 | 0 | 78 | 0 | 0 |
Antibiotics - Other quaternary ammonium compounds | 71 | 35 | 8 | 28 | 0.39 |
Penicillins with extended spectrum - Tetracyclines | 63 | 0 | 58 | 5 | 0.08 |
Protein kinase inhibitors - Triazole derivatives | 60 | 32 | 10 | 18 | 0.30 |
Beta blocking agents, non-selective - Sulfonamides, urea derivatives | 56 | 10 | 14 | 32 | 0.57 |
Macrolides - Protein kinase inhibitors | 56 | 27 | 14 | 15 | 0.27 |