Table 6 Top DDI Pairs found in Prescription Data

Amlodipine-Simvastatin

76980

X

Glipizide-Metoprolol

15469

X

X

atorvastatin-Fenofibrate

14897

X

X

Fenofibrate-Simvastatin

14060

X

X

Albuterol-Metoprolol

14030

X

Insulin Glargine-Metoprolol

13492

X

Metoprolol-Sertraline

13311

X

atorvastatin-Diltiazem

13218

X

X

Digoxin-Furosemide

12958

X

Lisinopril-Triamterene

12399

X

X

cyclobenzaprine-Tramadol

12211

X

Diltiazem-Metoprolol

11738

X

Oxycodone-Sertraline

11710

X

Diltiazem-Simvastatin

11484

X

X

Alprazolam-Fluoxetine

11194

X

Sertraline-Trazodone

11066

X

Amoxicillin-Ethinyl Estradiol

11044

X

Lisinopril-Spironolactone

10248

X

X

Clonazepam-Fluoxetine

10149

X

Fenofibrate-rosuvastatin

9954

X

X

Clonidine-Metoprolol

9827

X

X

Hydralazine-Metoprolol

9556

X

duloxetine-Trazodone

9236

X

clopidogrel-pantoprazole

9177

X

Escitalopram-Metoprolol

8396

X

Levofloxacin-Prednisone

8335

X

Escitalopram-Oxycodone

8228

X

Citalopram-Trazodone

8081

X

Citalopram-Oxycodone

8016

X

Metoprolol-salmeterol

7703

X

Atenolol-Glipizide

7597

X

X

Fluoxetine-Trazodone

7579

X

carvedilol-Digoxin

7517

X

Fluoxetine-Oxycodone

7508

X

carvedilol-Insulin Glargine

7496

X

Citalopram-Metoprolol

7474

X

Escitalopram-Trazodone

7421

X

Alprazolam-Omeprazole

7339

X