Fig. 2

Federated search using multiple SPARQL endpoints of the BMRB, UniProt, and OMIM. a An example of a SPARQL query begins from the BMRB entry. b Results performed by the SPARQL query for BMRB entry 4280, showing the BMRB ID, mutation, OMIM ID, dbSNP ID, secondary structure, and SASA. c Ribbon models of NMR structure (PDB: 1QK9) of MECP2. The side-chains (space-filling model) for the mutation (E137 and A140) exposed to solvent are responsible for X-linked mental retardation [18]