NeuroRDF: semantic integration of highly curated data to prioritize biomarker candidates in Alzheimer's disease

Table 2 Prioritized AD candidate genes

Intersected genes between healthy and AD PPI	MiRNAs	Differentially expressed neighbors		Number of literature articles for intersected genes
Intersected genes between healthy and AD PPI	MiRNAs	Healthy PPI	AD PPI	Number of literature articles for intersected genes
APP	MIR101-1,	ADAM10,	TGFB1,
	MIR106A,	MAPT,	BACE1,
	MIR106B,	MIF,	LRP1
	MIR124-1,	BACE1,		24550
	MIR137,	LRP1
	MIR153-1,
	MIR181-C,
	MIR29A,
	MIR520C,
	MIR19-1
BACE1	MIR107,
	MIR124-1,		APP,
	MIR145,	APP	LRP1	1883
	MIR298,
	MIR29A,
	MIR29B1,
	MIR328,
	MIR9-1
ADAM10	MIR451,
	MIR144,
	MIR1306,	APP	-	231
	MIR107,
	MIR103
IL1B	MIR146A,
IL1B	MIR155	PTGS2	-	1099
MAPK3	MIR15A,	-	STMN2,	276
MAPK3	MIR155	-	JUN	276
MAPT	MIR16-1,	APP	TUBA4A	3367
MAPT	MIR132	APP	TUBA4A	3367
APLP2	MIR153-1	-	-	134
DLG4	MIR485	-	LRP1	151
IL6	MIR27B	-	-	748
JUN	MIR144	-	STAT4,	142
JUN	MIR144	-	MAPK3	142
LRP1	MIR205	APP	DLG4,	305
			APP,
			BACE1
PTGS2	MIR146A	IL1B	-	474
TGFB1	MIR155	-	APP	276

This table summarizes the literature based evidences of intersected genes between healthy and AD PPI and their corresponding miRNAs and differentially expressed genes

ISSN: 2041-1480