Table 2 SNOMED CT relationships that were used to define the Dione classes

The part of the body affected by a condition

Represents a sequence of events where a clinical finding occurs after another

Represents a clinically relevant association between concepts without either asserting or excluding a causal or sequential relationship between the two

Identifies the direct causative agent of a disease (e.g., an organism)

Relates a clinical finding directly to a cause such as another clinical finding or a procedure

Links concepts in the situation with explicit context hierarchy to their related clinical finding

Specifies the morphologic changes seen at the tissue or cellular level that are characteristic features of a disease

Links disorders to the manifestations (observations) that define them

Refers to a specific period of life during which a condition first presents

Provides information about the underlying pathological process for a disorder, but only when the results of that process are not structural and cannot be represented by the associated morphology relationship

Refers to the entity being evaluated or interpreted, when an evaluation, interpretation or judgment is intrinsic to the meaning of a concept

Represents a sequence of events where a clinical finding occurs after another clinical finding or a procedure