Skip to main content

Table 1 TNM classification descriptors and additional modifiers

From: TNM-O: ontology support for staging of malignant tumours

Descriptor

Values

Meaning

T

0-4, is, X

Extent of the primary tumour

N

0-3, X

Extent of metastasis in regional lymph nodes

M

0-1

Existence of distant metastasis

Prefix to T, N, M

p, c

Clinical (pre-therapeutical) or pathological (post-surgical assessment)

Suffix to pNn

(mi)

Micrometastasis (< 0.2 cm)

Suffix to pNn

(sn)

Sentinel lymph node metastasis

Suffix to pN0 or pM0

(i+), (mol+)

Isolated tumour cells, positive findings

G

X, 1-4

Histopathological grading

Suffix to T

(m)

Multiple primary tumours at a single side

Prefix to c/ p

y

Assessment during multimodal therapy

Prefix to c/ p

r

Recurrent tumour

Prefix to c/ p

a

Assessment during autopsy

L

X, 0-1

Lymphatic invasion

V

X, 0-2

Venous invasion

Pn

X, 0-1

Perineural invasion

C

1-5

Validity of the assessment, can follow each of T, N, M

R

X, 0-2

Residual tumour

  1. Depending on the organ of the primary tumour, T, N, and M values can be further subdivided into levels a-c, e.g. N1a-c, N2a-c, and M1a-b in colorectal tumours