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Table 3 Comparison on the target-disease association data in the Target Validation Platform (release 1.2)

From: Literature evidence in open targets - a target validation platform

Evidence Type

Total number of distinct target-disease associations

Overlapping target-disease association

Total number of exclusively identified associations

Gene

Expression

Genetic

Associations

Affected

Pathways

Animal Models

Somatic Mutations

Known Drugs

Literature Mining

1,168,365

197,943

56,228

2506

99,836

19,801

19,811

850,179

Gene Expression

909,960

X

18,945

901

35,616

32,795

9913

669,330

Genetic Associations

129,826

X

X

1912

26,504

3626

2133

62,999

Affected Pathways

3613

X

X

X

1045

310

163

714

Animal Models

602,995

X

X

X

X

2965

4421

486,167

Somatic Mutations

58,941

X

X

X

X

X

1845

16,197

Known Drugs

57,319

X

X

X

X

X

X

33,005

  1. Total number of distinct target-disease associations in the platform is 2,485,000