Skip to main content

Table 4 Example new classes in DIDEO for NPDI

From: Extending the DIDEO ontology to include entities from the natural product drug interaction domain of discourse

Label

Textual definition

ID (DIDEO_)

Axiom

E. coli recombinant protein production host cell

a cultured cell of the species Escherichia coli that bears a recombinant protein production host role

00000169

‘cultured cell’ and ‘Escherchia coli’ and ‘bearer of’ some ‘recombinant protein production host role’

siRNA knockout Caco-2 cell

a Caco-2 cell that is a specified output of a gene knockout that has specified input siRNA

00000188

‘Caco-2 cell’ and is_specified_output_of some (‘gene knock out’ and has_specified_input some ‘siRNA oligonucleotide’)

293 transfected cell

a 293-derived cell that is a specified output of a transfection

00000189

‘293-derived cell’ and is_specified_output_of some transfection

omeprazole 5-hydroxylation

a hydroxylation that has omeprazole as input and has 5-hydroxyomeprazole as output

00000175

hydroxylation and ‘has input’ some omeprazole and ‘has output’ some 5’-hydroxyomeprazole

7-ethoxyresorufin O-deethylation

a deethylation that has 7-ethoxyresorufin as input and resorufin as output

00000172

deethylation and ‘has input’ some 7-ethoxyresorufin and ‘has output’ some resorufin