Skip to main content

Table 4 Example new classes in DIDEO for NPDI

From: Extending the DIDEO ontology to include entities from the natural product drug interaction domain of discourse

Label Textual definition ID (DIDEO_) Axiom
E. coli recombinant protein production host cell a cultured cell of the species Escherichia coli that bears a recombinant protein production host role 00000169 ‘cultured cell’ and ‘Escherchia coli’ and ‘bearer of’ some ‘recombinant protein production host role’
siRNA knockout Caco-2 cell a Caco-2 cell that is a specified output of a gene knockout that has specified input siRNA 00000188 ‘Caco-2 cell’ and is_specified_output_of some (‘gene knock out’ and has_specified_input some ‘siRNA oligonucleotide’)
293 transfected cell a 293-derived cell that is a specified output of a transfection 00000189 ‘293-derived cell’ and is_specified_output_of some transfection
omeprazole 5-hydroxylation a hydroxylation that has omeprazole as input and has 5-hydroxyomeprazole as output 00000175 hydroxylation and ‘has input’ some omeprazole and ‘has output’ some 5’-hydroxyomeprazole
7-ethoxyresorufin O-deethylation a deethylation that has 7-ethoxyresorufin as input and resorufin as output 00000172 deethylation and ‘has input’ some 7-ethoxyresorufin and ‘has output’ some resorufin