Ontology-based literature mining and class effect analysis of adverse drug reactions associated with neuropathy-inducing drugs

Table 2 The centrality scores of the ADRs in the NID specific ADR-ADR network

ADR	Degree	Eigenvector
nausea	27	0.311
headache	26	0.310
vomiting	23	0.301
diarrhoea	23	0.301
pruritus	19	0.270
dizziness	16	0.245
pyrexia	14	0.231
rash	14	0.231
thrombocytopenia	14	0.228
nervousness	13	0.222
asthenia	13	0.214
acute lymphocytic leukaemia	10	0.187
decreased appetite	10	0.177
insomnia	8	0.149
depression	8	0.148
urticaria	7	0.139
hypersensitivity	7	0.138
leukopenia	7	0.137
abdominal pain	6	0.122
dyspepsia	6	0.118
constipation	6	0.114
neuropathy peripheral	5	0.102
seizure	4	0.086
somnolence	4	0.086
paraesthesia	2	0.044
myalgia	2	0.044
arthralgia	2	0.041
alopecia	1	0.022
hyperhidrosis	1	0.022

Two centrality measures (degree and eigenvector) were calculated using Cytoscape app CentiScaPe

ISSN: 2041-1480