Skip to main content

Table 1 Characteristics of the two reference sets

From: Using predicate and provenance information from a knowledge graph for drug efficacy screening

Characteristics Guney reference set EMC reference set
Source of drug-disease indications MEDI-HPS + Metab2MeSH + manual curation MEDI-HPS [23]
Drug target sets 238 314
Unique drug targets 384 539
Source of drug targets DrugBank Santos et al. [25]
Disease protein sets 78 281
Unique disease proteins 2726 3205
Minimum size of disease protein set 20 1
Median size of disease protein set 52 5
Maximum size of disease protein set 606 273
Source of disease proteins OMIM + GWAS DisGeNet, curated subset [26]
Number of positive cases 402 1250
Number of negative cases 18,162 86,984