Table 2 Summary of articles discussing glutamate and epilepsy
Study | Subjects | Method | Result/Conclusion |
|---|---|---|---|
Juhász et al. [50] | Epileptic children with Sturge-Weber syndrome | Proton magnetic resonance spectroscopic brain imaging | Increased glutamate concentrations observed |
Cavus et al. [52] | Epileptic and nonepileptic cortical sites in patients with refractory epilepsy | High-performance liquid chromatography based on microdialysis probes | Elevated extracellular glutamate observed at epileptogenic sites |
Perez et al. [53] | Tissue extracted from brains of male Sprague Dawley rats infused with methionine sulfoximine | Glutamate levels measured with immunogold electron microscopy | Glutamine synthetase deficiency leads to increased extracellular glutamate |