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Table 9 Extension of IDO-COVID-19 from CIDO

From: The Infectious Disease Ontology in the age of COVID-19

Term

Definition

COVID-19

Coronavirus disease inhering in a SARS-CoV-2 disorder.

COVID-19 disease course

Coronavirus disease course that is the realization of some COVID-19 disease and has participant SARS-CoV-2.

pathogenesis (GO)

Process that generates the ability of a pathogen to induce a disorder in an organism.

coronavirus pathogenesis (CIDO)

Virus pathogenesis that is the realization of an infectious disposition inhering in a coronavirus or coronavirus population, having at least the process parts: (1) pathogen transmission, (2) establishment of localization in host, (3) process of establishing an infection, and (4) appearance of a virus disorder.

SARS-CoV-2 pathogenesis

Coronavirus pathogenesis process that is the realization of an infectious disposition inhering in SARS-CoV-2 or a SARS-CoV-2 population, having at least the proper process parts: (1) pathogen transmission, (2) establishment of localization in host, (3) process of establishing an infection, and (4) appearance of a virus disorder.

replication (IDO Core)

Production process in which a participant creates a copy of itself.

virus replication (VIDO)

Replication process in which a virus containing some portion of genetic material inherited from a parent virus is replicated.

generative stage (IDO Core)

Temporal subdivision of a developmental process.

virus generative stage (VIDO)

Infectious structure generative stage that is a temporal subdivision of a virus developmental process.

virus attachment stage (VIDO)

Virus generative stage during which a virion protein binds to molecules on the host surface or host cell surface projection.

virus penetration stage (VIDO)

Virus generative stage during which a virion or viral nucleic acid breaches the barriers of a host.

SARS-CoV-2 attachment stage

Virus attachment stage during which SARS-CoV-2 bonds with a host cell.

SARS-CoV-2 penetration stage

Virus penetration stage during which SARS-CoV-2 penetrates a host cell.

SARS-CoV-2 adhesion susceptible cell

Virus adhesion susceptible cell with a functional receptor part bearing an adhesion disposition realized in a SARS-CoV-2 attachment stage.

SARS-CoV-2 penetration disposition

Virus penetration disposition borne by a functional receptor complex that is the disposition to participate in a SARS-CoV-2 penetration process.

negative regulation of SARS-CoV-2 attachment

Negative regulation of coronavirus replication process that stops, prevents, or reduces the frequency of some SARS-CoV-2 attachment stage.

negative regulation of SARS-CoV-2 penetration

Negative regulation of coronavirus replication that stops, prevents, or reduces the frequency of some SARS-CoV-2 penetration stage.