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Table 3 Evolution statistics for selected biomedical ontologies

From: GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution

Name

O0

On

|Co|

|Cn|

growthC

|R0|

|Rn|

growthR

growthC+R

Protein Protein Interaction Ontology

2005-08

2009-06

194

960

4.95

211

1,006

4.77

4.85

Biological Processes (GO)

2002-12

2010-03

6,741

19,099

2.83

0

39,391

 

8.68

NCI Thesaurus

2003-10

2009-12

28,740

77,448

2.69

33,847

86,803

2.56

2.62

Cellular Components (GO)

2002-12

2010-03

1,124

2,810

2.50

0

5,185

 

7.11

Chemical Entities of biomedical Interest

2004-10

2009-08

10,236

24,225

2.37

11,592

43,085

3.72

3.08

Mammalian Phenotype Ontology

2005-08

2010-03

4,175

7,571

1.81

4,620

8,560

1.85

1.83

Sequence Ontology

2005-08

2010-03

981

1,764

1.80

1,181

2,014

1.71

1.75

Molecular Functions (GO)

2002-12

2010-03

5,298

9,487

1.79

0

10,972

 

3.86

Pathway Ontology

2005-11

2010-03

427

751

1.76

478

923

1.93

1.85

Zebrafish Anatomy

2005-11

2009-12

1,389

2,431

1.75

4,272

8,819

2.06

1.99

Cell Type Ontology

2004-06

2010-01

687

1,049

1.53

1,251

1,799

1.44

1.47

Plant Structure Ontology

2005-07

2009-08

681

868

1.27

980

1,274

1.30

1.29

Protein Modification Ontology

2006-06

2009-02

1,074

1,338

1.25

1,568

1,982

1.26

1.26

Adult Mouse Anatomy

2005-08

2010-03

2,416

2,947

1.22

2,939

3,722

1.27

1.25

Fly Anatomy

2004-12

2010-02

6,090

6,707

1.10

9,826

12,319

1.25

1.20

Flybase Controlled Vocabulary

2004-12

2010-02

658

713

1.08

653

698

1.07

1.08

  1. The table shows evolution statistics of analyzed ontologies taking different evolution measures such as the growth rate or the number of concepts/relationships into account. (|R| - number of relationships, |C| - number of concepts)