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Table 3 Evolution statistics for selected biomedical ontologies

From: GOMMA: a component-based infrastructure for managing and analyzing life science ontologies and their evolution

Name O0 On |Co| |Cn| growthC |R0| |Rn| growthR growthC+R
Protein Protein Interaction Ontology 2005-08 2009-06 194 960 4.95 211 1,006 4.77 4.85
Biological Processes (GO) 2002-12 2010-03 6,741 19,099 2.83 0 39,391   8.68
NCI Thesaurus 2003-10 2009-12 28,740 77,448 2.69 33,847 86,803 2.56 2.62
Cellular Components (GO) 2002-12 2010-03 1,124 2,810 2.50 0 5,185   7.11
Chemical Entities of biomedical Interest 2004-10 2009-08 10,236 24,225 2.37 11,592 43,085 3.72 3.08
Mammalian Phenotype Ontology 2005-08 2010-03 4,175 7,571 1.81 4,620 8,560 1.85 1.83
Sequence Ontology 2005-08 2010-03 981 1,764 1.80 1,181 2,014 1.71 1.75
Molecular Functions (GO) 2002-12 2010-03 5,298 9,487 1.79 0 10,972   3.86
Pathway Ontology 2005-11 2010-03 427 751 1.76 478 923 1.93 1.85
Zebrafish Anatomy 2005-11 2009-12 1,389 2,431 1.75 4,272 8,819 2.06 1.99
Cell Type Ontology 2004-06 2010-01 687 1,049 1.53 1,251 1,799 1.44 1.47
Plant Structure Ontology 2005-07 2009-08 681 868 1.27 980 1,274 1.30 1.29
Protein Modification Ontology 2006-06 2009-02 1,074 1,338 1.25 1,568 1,982 1.26 1.26
Adult Mouse Anatomy 2005-08 2010-03 2,416 2,947 1.22 2,939 3,722 1.27 1.25
Fly Anatomy 2004-12 2010-02 6,090 6,707 1.10 9,826 12,319 1.25 1.20
Flybase Controlled Vocabulary 2004-12 2010-02 658 713 1.08 653 698 1.07 1.08
  1. The table shows evolution statistics of analyzed ontologies taking different evolution measures such as the growth rate or the number of concepts/relationships into account. (|R| - number of relationships, |C| - number of concepts)