Figure 1

Schematic representation of the prognosis methodology. The methodology is composed by two units: the first (left-side) receives as input data from patients mapped to biomedical ontologies/controlled vocabularies. It performs an enrichment analysis to identify a list of ontology terms considered to be enriched, which will be used to create profiles for individual patients. These profiles will then be subjected to an evaluation step (the second unit, on the right-side) that will result in the evaluation of the prognosis for the patients. For the implementation of the second unit, both a classification and a similarity approach will be explored.