Figure 2

Graphical representation of results of the SPARQL query for CTD chemicals that participate in the same molecular process as SGD proteins. The SGD gene S000004901 encodes a gene product that is typed as ‘protein’ in the SGD dataset. This protein is annotated to be a participant in the GO process “RNA splicing”. Chemicals from the CTD dataset that are also participants in this GO process are retrieved. This query is possible because of cross-dataset links between CTD and SGD that result from mapping their Bio2RDF vocabularies to SIO: the SGD type ‘protein’ was mapped as a subclass of the SIO ‘protein’ class, while the CTD type ‘chemical’ was mapped as a subclass of the SIO ‘chemical entity’ class. The SGD dataset uses SIO relation ‘encodes’ to relate genes and gene products, and both the SGD and CTD datasets use the SIO relation ‘is participant in’ to link entities to GO processes. Square boxes are SIO OWL classes. Rounded boxes are RDF resources that are part of Bio2RDF linked datasets.