The hierarchies of over- and under-represented INO interaction terms. (A) The hierarchy of 14 over-represented INO interaction terms. (B) The hierarchy of 17 under-represented INO interaction terms. The results were generated using OntoFox  with the OntoFox setting “includeComputedIntermediates”, and visualized using the Protege-OWL editor (http://protege.stanford.edu/). The box-enclosed terms are over- or under-represented interaction types directly identified in our program (see Tables 2 and 3). Other terms not enclosed in boxes are terms retrieved by OntoFox to ensure the completeness of the hierarchies.