Table 4 Logic facts definition for drug drug interaction inference
From: Extracting drug-enzyme relation from literature as evidence for drug drug interaction
Drug enzyme relation | |
isSubstrateOf (d, e) | Drug d is metabolized by enzyme e |
isInhibitorOf (d, e) | Drug d inhibits the activity of enzyme e |
isInducerOf (d, e) | Drug d induces the activity of enzyme e |
Enzyme enzyme relation | |
isAncestorOf (e1, e2) | Enzyme e1 is an ancestor of enzyme e2 in the enzyme family |
Drug drug relation | |
DDI(d1, d2) | Drug d1 and drug d2 have an interaction |