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Table 8 A comparison between DMTO and some existing diabetes treatment ontologies

From: DMTO: a realistic ontology for standard diabetes mellitus treatment

Dimension DMTO DKOs [21] Chen et al. [14] Chalortham et al. [34] Zhang et al. [35] OntoDiabetic [33]
Purpose Treatment Treatment Treatment Treatment Treatment Treatment
Available for reuse Yes No No No No No
Based on a unified top-level ontology Yes No No No No No
Encoded using standardized terminology Yes No No No Yes No
Based on OWL 2 and SWRL Yes Yes Yes Yes Yes Yes
Interoperable with EHR systems Yes No No No Yes No
Decisions based on the whole patient profile Yes Yes Only 6 tests entered by user No Yes Yes
Based on standard knowledge (e.g., collected from CPGs) Yes No Yes No Yes Yes
Uses a systematic method for creation Yes No No Yes No No
Delivers treatment plans with drugs, lifestyle, and education Yes No No No Yes No
Models diabetes drugs Yes No Yes No No Yes
Models drugs affecting glucose level Yes No No No No No
Models drug properties Yes No Yes No No No
Models T2DM comorbidities Yes Yes No No No Yes
Reuses existing ontologies Yes No No Yes No Yes
Ontology coverage (number of classes, properties, axioms, and rules) Table 10 NA 18 drugs +6 rules NA NA NA
Models temporal semantics Yes No Yes No No No