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Table 2 Top ranked predicted mappings for Reactome pathway R-HSA-109581, “Apoptosis”

From: Predicting instances of pathway ontology classes for pathway integration

 

PW ID

PW class name

Beginning of definition text

1

PW_0000104

intrinsic apoptotic pathway

The apoptotic pathway involving organelles, primarily the mitochon...

2

PW_0000009

apoptotic cell death pathway

Apoptosis is a programmed cell death pathway that is characterized by...

3

PW_0000106

extrinsic apoptotic pathway

The apoptotic pathway involving the death receptors mediated route of...

4

PW_0000718

p53 signaling pathway

p53 transcription factor is a tumor suppressor frequently mutated in...

5

PW_0000124

cellular detoxification pathway

A pathway triggered by exogenous or endogenous elements, compounds...

6

PW_0000823

humoral immunity pathway

Humoral immunity is mediated by antibodies secreted by the B cell...

7

PW_0000824

cell-mediated immunity pathway

Cell-mediated immune response pathways are carried out by T cell...

8

PW_0000499

nuclear factor kappa B signaling pathway

NF-kB signaling plays an essential role in the mammalian immune...

9

PW_0000680

altered extrinsic apoptotic pathway

<no definition >

10

PW_0000233

tumor necrosis factor mediated signaling pathway

Tumor necrosis factor (Tnf) signaling plays pivotal roles in immunity...