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Table 2 Top ranked predicted mappings for Reactome pathway R-HSA-109581, “Apoptosis”

From: Predicting instances of pathway ontology classes for pathway integration

  PW ID PW class name Beginning of definition text
1 PW_0000104 intrinsic apoptotic pathway The apoptotic pathway involving organelles, primarily the mitochon...
2 PW_0000009 apoptotic cell death pathway Apoptosis is a programmed cell death pathway that is characterized by...
3 PW_0000106 extrinsic apoptotic pathway The apoptotic pathway involving the death receptors mediated route of...
4 PW_0000718 p53 signaling pathway p53 transcription factor is a tumor suppressor frequently mutated in...
5 PW_0000124 cellular detoxification pathway A pathway triggered by exogenous or endogenous elements, compounds...
6 PW_0000823 humoral immunity pathway Humoral immunity is mediated by antibodies secreted by the B cell...
7 PW_0000824 cell-mediated immunity pathway Cell-mediated immune response pathways are carried out by T cell...
8 PW_0000499 nuclear factor kappa B signaling pathway NF-kB signaling plays an essential role in the mammalian immune...
9 PW_0000680 altered extrinsic apoptotic pathway <no definition >
10 PW_0000233 tumor necrosis factor mediated signaling pathway Tumor necrosis factor (Tnf) signaling plays pivotal roles in immunity...