Table 3 Sample of manually analyzed disease terms predicted as infectious disease
From: Combining lexical and context features for automatic ontology extension
Disease terms | Ontology class assigned by ANN | Manual analysis result | Suggested additional classification | DOID | Explanation |
|---|---|---|---|---|---|
Pelizaeus-Merzbacher disease | Viral infectious disease | Non-infectious (inherited disorder) | - | - | - |
Kaposi’s sarcoma | Viral infectious disease | Viral infectious disease | herpes simplex | DOID:8566 | The disease is caused by Human herpesvirus 8 which is Herpesviridae infection. |
maxillary sinusitis | Bacterial infectious disease | Bacterial infectious disease (usually start viral and progress to either bacterial or fungal) | - | - | It is an infection in the maxillary sinuses which could be due to different etiology, one of them is bacterial [47]. |
keratosis follicularis | Bacterial infectious disease | Non-infectious (genetic disease) | - | - | - |
chronic rheumatic pericarditis | Viral infectious disease | The condition is triggered by autoimmune reaction to infection, mainly group A streptococci. | - | - | - |
gastroparesis | Viral infectious disease | In most cases the nerve is damaged by diabetes or surgery, however, a viral infection might be a cause | - | - | A condition in which the stomach suffers from paresis that affects the food movement to the small intestine [48, 49]. |
osmotic diarrhea | Bacterial infectious disease | symptom | - | - | - |
familial cold autoinflammatory syndrome | Viral infectious disease | Non-infectious (inherited disease) | - | - | - |
angular cheilitis | Fungal infectious disease | Etiology is controversial, most commonly fungal or bacterial. | - | - | Ambiguous. |
Binder syndrome | Viral infectious disease | Congenital disease | - | - | - |
hypohidrosis | Bacterial infectious disease | Multi-causal | - | - | - |
Sjogren’s syndrome | Viral infectious disease | autoimmune disease | - | - | - |
median rhomboid glossitis | Fungal infectious disease | Etiology is controversial, however it is considered as a variant of orallesion associated with candida infection [50]. | - | - | Ambiguous. |
Goodpasture syndrome | Viral infectious disease | autoimmune disease | - | - | - |
syphilitic meningitis | Bacterial infectious disease | Bacterial infectious disease | syphilis | DOID:4166 | Considering the same concept of etiology, both diseases are caused by bacterial infection (Treponema pallidum). |
acute diarrhea | Viral infectious disease | symptom | - | - | - |
WHIM syndrome | Bacterial infectious disease | Congenital disease | - | - | - |
erythrasma | Fungal infectious disease | Bacterial infection disease | - | - | - |
chronic wasting disease | Parasitic infectious disease | Neurodegenerative disorder | - | - | - |
scarlet fever | Bacterial infectious disease | Bacterial infectious disease | rheumatic fever | DOID:1586 | The disease is caused by Group A bacteria of the genus Streptococcus, same causative agent for Rheumatic fever. |