Fig. 4

This figure present the workflow of this work with the example of the phenotype (increased number of T Cells) and the phenotype (absent T Cells). In this particular example, we created the class (collection of T cells) representing all the T cells. Then we created the phenotype classes (increased number of T Cell within a collection) and (absence of all T Cells). We added two structuring classes, one based on the quality (increased amount) and one based on the collection (collection of T cell). In order to evaluate, we applied a quantitative evaluation based on a biomedical task, in particular the gene–disease association prediction task using semantic similarity between phenotypes