Fig. 3
From: Ontological representation, modeling, and analysis of parasite vaccines
ODP of parasite vaccine within VO. (A) The Ontology design pattern (ODP) of transmission blocked parasite vaccines within VO. Currently all blocked transmission vaccines in VO are also parasite vaccines. (B) Representation of parasite antigen PfCelTOS (P. falciparum cell traversal in sporozoite and ookinetes) and (C) Pfcs (P. falciparum circumsporozoite protein) within VO. Pfcs is currently used in the only licensed malaria vaccine despite only targeting one life stage. PfCelTOS is found in multiple life stages and thus may have a greater range of targets