Figure 4

The phenotype annotation process in GWAS Central as applied to three different phenotypes. Manual annotations are made using the GWAS Central curation tool. Solid black lines denote direct manual annotations and the dotted black lines denote automatically mapped annotations. ‘Phenotype A’ is manually annotated with a more specific term from HPO. ‘Phenotype B’ is annotated with MeSH and the HPO term is automatically mapped. ‘Phenotype C’ is annotated with a MeSH disease Descriptor and is mapped to the inferred HPO phenotypic abnormalities via OMIM.